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Friday, 1 March 2013

Physiology

Human insulin is a naturally occurring peptide hormone. It is composed of two peptide chains, the ?-chain and ?-chain. They atomic number 18 linked to followher by disulfide bonds. The ?-chain consists of 21 amino group acids and the ?-chain of 30 amino acids giving a total of 51 amino acids. It is exclusively synthesized in the pancreas within the ?-cells of the islets of Langerhans.
Glucose liberated from dietary kale is absorbed into the blood. Increased densenesss of glucose in blood stimulate carrier bag of insulin from the pancreatic beta cells. The effect of insulin is to decrease the concentration of glucose in blood. It acts on cells throughout the body to stimulate uptake, utilization and reposition of glucose. The effects of insulin on glucose metabolism vary depending on the marking tissue. Insulin facilitates entry of glucose into muscle, adipose and several early(a) tissues while it stimulates the liver-colored to store glucose in the form of glycogen. Without insulin, a person fecal matter eat lots of food and actually be in a state of starvation since m either of the cells cannot access the calories contained in the glucose very well without the action of insulin.

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As the blood glucose concentration starts coming back to normal the beta cells become slight and less stimulated and so the rate of secretion of insulin declines in parallel to the rate of decline in blood glucose concentration.
Auto-immune solvent in the body physically destroys the beta cells. In other words, abnormal proteins get into the blood and in the bodys attempts to destroy the proteins the beta cells in the pancreas are destroyed. Sometimes the beta cell serve well is impaired. As a result the pancreas does not make adequate insulin. This leads to a condition known as diabetes. Diabetes is a ailment that is multi-systematic. It affects the blood vessels and nerves and therefore can affect any part of the body. Hence it needs to be treated.
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